In Vitro Biomechanical Testing of Two Injectable Materials for Vertebroplasty in Different Synthetic Bones
Two different injectable materials, intended for use in vertebroplasty (VP) treatments of fractured vertebras, were tested in an in vitro bone model. The materials tested were an experimental bioceramic material based on calcium aluminate manufactured by Doxa AB, and Vertebroplastic, a PMMA based material manufactured by DePuy Acromed. The model was earlier developed by others and has been found valid for testing of materials intended for PVP. The model offers alternative data to traditional compressive and diametral tensile testing by adding the infiltration of material into synthetic cancellous bone. Five different synthetic bones with different porosity and pore structure were tested. The results show that for the PMMA the infiltration pattern of the different bones tested seems to have no influence. The material deforms plastically and displays about the same strength in all bones tested. For the bioceramic, linear elastic, material however there is a difference. In the more porous bones, where the material infiltrate the pores and creates a test body with a large amount of crack initiation points, the material displays lower strength compared to that of the more solid bones.
Guy Daculsi and Pierre Layrolle
J. Lööf et al., "In Vitro Biomechanical Testing of Two Injectable Materials for Vertebroplasty in Different Synthetic Bones", Key Engineering Materials, Vols. 361-363, pp. 369-372, 2008