Preparation and Evaluation of Nano-Hydroxyapatite/β-Tricalcium Phosphate/Chitosan Composite Scaffolds for Bone Tissue Engineering
The composite scaffolds with nine different ratios of nano-HA and ß-TCP content were fabricated by using lyophilization method. Their microscopy, physical and chemical properties were investigated by using scanning electron microscopy (SEM), X-ray diffraction (XRD), and fourier transformed infrared (FTIR) spectroscopy. MTT test was applied to quantitatively assess the number of viable cells attached and grown on the scaffolds. And the result showed that the amount of cells on the scaffold containing 30% by mass of nano-HA was significantly higher than the other samples.
Guy Daculsi and Pierre Layrolle
T. Lin et al., "Preparation and Evaluation of Nano-Hydroxyapatite/β-Tricalcium Phosphate/Chitosan Composite Scaffolds for Bone Tissue Engineering", Key Engineering Materials, Vols. 361-363, pp. 463-466, 2008