Nanostructured Calcium Phosphate Coating for Stents
A nanoporous calcium phosphate (CaP) coating on metallic surfaces is presented. The coating consists of a stack of (a) a TiNbN layer deposited by physical vapor deposition and acting as diffusion barrier against allergenic ions, (b) a SiO2 xerogel layer providing good adhesion properties and designing the nanoporosity of the outer CaP layer (c) precipitated electrochemically. SEM results verified a homogeneous nanoscale porous structure of the CaP coating. It is characterized by a high adhesion strength. If applied to stent covering the nanoporous CaP coating has promising properties to initiate rapid endothelium formation and reduced risk of restenosis.
Guy Daculsi and Pierre Layrolle
U. Lembke et al., "Nanostructured Calcium Phosphate Coating for Stents", Key Engineering Materials, Vols. 361-363, pp. 721-724, 2008