Porous HA/TCP bioceramics were immersed in pure bovine serum to observe the growth and formation of apatite. HRTEM, FTIR, and SEM coupled with EDS were used for the characterization of immersed samples. SEM results showed that some beamed crystals formed on the surface of ceramics granules, and with postponement of immersion time, crystals extended and became bigger, strap-like crystals became sheet-like crystals. HRTEM observations indicated that new-formed crystals developed along axes direction according to parallel layers. IR spectrum showed CO3 2- characteristic peaks existed besides O-P-O and OH- characteristic peaks. EDS results showed that calcium and phosphor ratio was 1.95 (mol ratio). The results indicated that bovine serums were advantaged to bone-like apatite formation.