Biological Performance of Dental Biphasic Calcium Phosphate Ceramics Modified by Cold Plasma


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HA/ß-TCP is one kind of important bone tissue engineering scaffold materials. In order to improve the biological performance of materials, HA/ß-TCP ceramics were modified by the cold plasma technique in this paper. The biological performances of treated materials were evaluated by the results of bone-like apatite formation in SBF, the coculture of the C2C12 cell line and HA/ß-TCP, cell proliferation experiments, observations of the electron microscopy and fluorescence staining and the animal intramuscular implantation experiments. The results showed that after immersion, compared with untreated HA/ß-TCP, treated materials were more conducive to form bone-like apatite; modified HA/ß-TCP could promote the cell proliferation more; the cells grew in the course of nature on the treated scaffold and modified HA/ß-TCP had better bone-forming performance in vivo. It was concluded that modified HA/ß-TCP had better biological performance; the cold plasma technique could improve the biological performance of dental biphasic calcium phosphate ceramics.



Key Engineering Materials (Volumes 368-372)

Edited by:

Wei Pan and Jianghong Gong




B. H. Su et al., "Biological Performance of Dental Biphasic Calcium Phosphate Ceramics Modified by Cold Plasma", Key Engineering Materials, Vols. 368-372, pp. 1264-1267, 2008

Online since:

February 2008




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