A Combined Experimental-Computational Strategy for the Design, Synthesis and Characterization of Bioactive Zinc-Silicate Glasses


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This review presents a combined experimental-computational strategy for the development of potential bioactive zinc–containing silicate glasses and shows how sound relationships among the structural role of some key elements that appear to control bioactivity can by established and exploit for rational glass design.



Edited by:

Maria Vallet-Regí




G. Lusvardi et al., "A Combined Experimental-Computational Strategy for the Design, Synthesis and Characterization of Bioactive Zinc-Silicate Glasses", Key Engineering Materials, Vol. 377, pp. 211-224, 2008

Online since:

March 2008




[1] L. L Hench: J. Am. Ceram. Soc. Vol. 74 (1991), p.1487.

[2] M. Vallet-Regi: J. Chem. Soc. Dalton Trans. Vol. 2 (2001) p.97.

[3] U. Gross, R. Kinne, H.J. Schimit and V. Strunz: CRC Crit. Res. Biocompat. Vol. 4 (1998) p.2.

[4] S.F. Hulbert, L.L. Hench, D. Forbers and L.S. Bowmann: Ceram. Int. Vol. 8 (1982) p.121.

[5] L.L. Hench, R.J. Splinter, W.C. Allen and T.K. Greenlee: J. Biomed. Mater. Res. Vol. 2 (1972), p.117.

[6] D.G. Castner and B.D. Ratner: Surface Science Vol. 28 (2002), p.500.

[7] P. Ducheyne and Q. Qiu: Biomaterials Vol. 20 (1999), p.2287.

[8] A. Rosengren, , S. Oscarsson, , M. Mazzocchi, A. Krajewski, and A. Ravaglioli: Biomaterials Vol. 24 (2003), p.147.

DOI: 10.1016/s0142-9612(02)00272-7

[9] M. Brink: J. Biomed. Mater. Res. Vol. 36 (1997), p.109.

[10] M. Brink, T. Turunen, R.P. Happonen and A. Yli-Urpo: J. Biomed. Mater. Res. Vol. 37 (1997), p.114.

[11] L. Linati, G. Lusvardi, G. Malavasi, L. Menabue, M.C. Menziani, P. Mustarelli and U. Segre: J. Phys. Chem. B Vol. 109 (2005), p.4989.

DOI: 10.1021/jp046631n

[12] S.H. Garofalini, in Reviews in Mineralogy and Geochemistry Cygan, T. T, Kubicki, J. D. Editors, p.131, (2001).

[13] A.N. Cormack and Y. Cao: Mol. Eng. Vol. 6 (1996), p.6.

[14] G.N. Greaves, W. Smith and M.J. Gillan: J. Non-Cryst. Solids Vol. 192 (1995), p.267.

[15] C. Wang, N. Kuzuu and Y. Tamai: J. Non-Cryst. Solids Vol. 318 (2003), p.131.

[16] A. Abbas, J.M. Delaye, D. Ghaleb and G. Calas: J. Non-Cryst. Solids Vol. 315 (2003), p.187.

[17] D.A. Litton and S.H. Garofalini: J. Appl. Phys. Vol. 89 (2001), p.6013.

[18] E.A. Leed and C.G. Pantano: J. Non-Cryst. Solids Vol. 325 (2003), p.48.

[19] A.G. Clare, M.M. Hall, M.L. Korwin-Edson and A.H. Goldstein: J. Phys.: Condens. Matter Vol. 15 (2003), p. S2365-75.

[20] A.N. Cormack, R.J. Lewis and A.H. Goldstein: J. Phys. Chem. B Vol. 108 (2004), p.20408.

[21] N.H. De Leeuw, D. Mkhonto and R.C.A. Catlow: J. Phys. Chem. B Vol. 107 (2003), p.1.

[22] G. Lusvardi, G. Malavasi, L. Menabue, M.C. Menziani, A. Pedone and U. Segre: J. Phys. Chem. B Vol. 109 (2005), p.21586.

[23] G. Ennas, A. Musinu, G. Piccaluga, A. Montenero and G. Gnappi: J. Non-Cryst. Solids Vol 125 (1990), p.181.

DOI: 10.1016/0022-3093(90)90337-l

[24] E.C. Onyiriuka: J. Non-Cryst. Solids Vol. 168 (1993), p.268.

[25] A. Oki, B. Parveen, S. Hossain, S. Adeniji and H. Donahue: Journal of Biomedical Materials Research. Part A. Vol. 69(2) (2004), p.216.

[26] J. Brandao-Neto, V. Stefan, B.B. Mendonça, W. Bloise an A.V.B. Castro: Nutrition Research. Vol. 15 (1995), p.335.

[27] W.R. Holloway, F.M. Collier, R.E. Herbst, J.M. Hodge and G.C. Nicholson: Bone Vol. 19 (1996), p.137.

[28] M. Yamaguchi and R. Yamaguchi: Biochem Pharmacol. Vol. 35(5) (1986), p.773.

[29] S.F. Rosenstiel, M.F. Land and B.J. Crispin: Journal of Prosthetic Dentistry Vol. 80(3) (1998), p.280.

[30] T. Kokubo, H.M. Kim and M. Kawashita: Biomaterials Vol. 24(13) (2003), p.2161.

[31] H.M. Kim, F. Miyaji and T. Kokubo: J. Am. Ceram. Soc. Vol. 78 (1995), p.2405 and ref. therein.

[32] B. Vessal, In Amorphous solids - Computer Modelling in Inorganic Crystallography, edited by C.R.A. Catlow, Academic Press. Ltd (1997).

[33] A.N. Cormack and Y. Cao: Molecular Engineering Vol. 6 (1996), p.183.

[34] A. Pedone, G. Malavasi, M.C. Menziani, A.N. Cormack and U. Segre: J. Phys. Chem. B Vol. 110 (2006), p.11780.

[35] W. Smith and T.R. Forester: J. Mol. Graphics Vol. 14 (1996), p.136.

[36] G. Malavasi, A. Pedone and M.C. Menziani: Molecular Simulation Vol. 32(12-13) (2006), p.1045.

[37] A. Pedone, G. Malavasi, A.N. Cormack, U. Segre and M.C. Menziani: Chem. Mater. Vol. 19(13) (2007), p.3144.

[38] G. Lusvardi, G. Malavasi, L. Menabue, M.C. Menziani, A. Pedone, U. Segre, V. Aina, A. Perardi, C. Morterra, F. Boccafoschi, S. Gatti, M. Bosetti and M. Cannas: J. of Biomater. Appl. (2007), doi: 10. 1177/0885328207079731.

DOI: 10.1177/0885328207079731

[39] G. Lusvardi G. Malavasi, A. Pedone, L. Menabue, V. Bolis, M. Borsetto, F. Boocafoschi and M. Cannas, In Ceramic, Cells and Tissues, Materials for Scaffolding of Biologically engineered systems-Interface amd Interactions on a Nanoscale, edited by A. Ravaglioli, A. Krajewski CNR , Italy (2006).

[40] C. Riganti, C. Costamagna, A. Bosia and D. Ghigo: Toxicol. Appl. Pharmacol. Vol. 212 (2006), p.179.

[41] V.L. Kinnula, K. Aalto, K.O. Raivio, S. Walles and K. Linnainmaa: Free Radic. Biol. Med. Vol. 16 (1994), p.169.

[42] V. Aina, A. Perardi, L. Bergandi, G. Malavasi, L. Menabue, C. Morterra and D. Ghigo: Chimico-Biological Interactions Vol. 167 (2007), p.207.

DOI: 10.1016/j.cbi.2007.03.002

[43] G. Malavasi, G. Lusvardi, A. Pedone, M.C. Menziani, M. Dappiaggi, A. Gualtieri and L. Menabue: J. Phys. Chem. A Vol. 111(34) (2007), p.8401.

DOI: 10.1021/jp071528u

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