In Vivo Biological Behavior of Calcium Phosphate Cements with Different Ca/P Ratio

Abstract:

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Bioceramics with different Ca/P ratio were prepared from a mechanical mixture of NaPO3, CaCO3, Ca(OH)2 and phosphate buffer solution and implanted in rats subcutaneous tissues. The cements were characterized by Thermogravimetric analysis (TG-TDA), X-ray diffraction and 31P-NMR. The implant sites were excised after 1, 4 and 16 weeks, fixed, dehydrated, included in paraffin wax for serial cutting and examined under the light transmitted microscope. They were biocompatible and biodegradable when implanted in rat subcutaneous. None of the materials induced ectopic osteogenesis. According to the results, the studied materials seem to be able for manufacturing reabsorbable bone implants.

Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Main Theme:

Edited by:

Marcelo Prado and Cecília Zavaglia

Pages:

237-240

DOI:

10.4028/www.scientific.net/KEM.396-398.237

Citation:

S. Saska et al., "In Vivo Biological Behavior of Calcium Phosphate Cements with Different Ca/P Ratio", Key Engineering Materials, Vols. 396-398, pp. 237-240, 2009

Online since:

October 2008

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Price:

$35.00

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