Macroporous Calcium Phosphate Cement (MCPC®) for Bone Reconstruction in Cranioplasty: Animal Study Performance

Abstract:

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We have developed a novel macroporous calcium phosphate cement MCPC® that sets to poorly crystalline apatite after mixing the powder component with an aqueous solution and has interconnective macroporosity We performed cranioplasty on rat model by injecting the new macroporous calcium phosphate cement MCPC®. The mechanical property of the cement is about 12MPa after 24 hours (compression test). The cement matrix is totally transformed into poorly crystalline apatite in 48 hours. This study demonstrates that MCPC® cement was suitable and efficient for parietal bone reconstruction. Its injectability and moldability allows to be used in bone reconstruction surgery and its mechanical properties are compatible to support calvarial reconstruction. In addition, a bone ingrowth onto the BCP granules occurred on time.

Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Main Theme:

Edited by:

Marcelo Prado and Cecília Zavaglia

Pages:

245-248

DOI:

10.4028/www.scientific.net/KEM.396-398.245

Citation:

X. Bourges et al., "Macroporous Calcium Phosphate Cement (MCPC®) for Bone Reconstruction in Cranioplasty: Animal Study Performance", Key Engineering Materials, Vols. 396-398, pp. 245-248, 2009

Online since:

October 2008

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Price:

$35.00

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