Use of Complexing Agents in Hydroxyapatite Synthesis
Production of calcium phosphates from homogeneous solutions of Ca2+ and PO43- are studied in presence of complexing agents such as acetic acid, lactic acid, etilendiaminotetracetic acid (EDTA), iminodietanoic acid, and malic acid; solids are characterized with infrared spectroscopy (IR), powder x-ray diffraction, scanning electron microscopy (SEM) and electron dispersion spectra (EDS). The objective for this experiment was to find a suitable complexing agent to produce hydroxyapatite under mild reaction conditions. With the methodology described only tree phases are produced: brushite, monetite and hydroxyapatite. It is found a relationship among the ligand and the calcium phosphate phase obtained, where the complexing agent that provides the best working conditions for hydroxyapatite production is EDTA.
Marcelo Prado and Cecília Zavaglia
H. Arce and M. L. Montero, "Use of Complexing Agents in Hydroxyapatite Synthesis", Key Engineering Materials, Vols. 396-398, pp. 293-296, 2009