The aim of this study is to investigate the creep-fatigue behavior of stainless steel materials. Based on the elevated-temperature tensile, creep and rupture test data, thermal creep-fatigue modelling was conducted to predict the failure life of stainless steels. In the low cycle thermal fatigue life model, Manson’s Universal Slopes equation was used as an empirical correlation which relates fatigue endurance to tensile properties. Fatigue test data were used in conjunction with different modes to establish the relationship between temperature and other parameters. Then creep models were created for stainless steel materials. In order to correlate the results of short-time elevated temperature tests with long-term service performance at more moderate temperatures, different creep prediction models, namely Basquin model, Sherby-Dorn model and Manson-Haferd model, were studied. Comparison between the different creep prediction models were carried out for a range of stresses and temperatures. A linear damage summation method was used to establish life prediction model of stainless steel materials under creep-fatigue.