Fatigue properties of the new generation of TiAl alloys with 8at.% of Nb were studied and compared with those reported in the literature for previous generation with 2at.% of Nb. The high Nb content improves substantially the fatigue life time in the Basquin representation. Nevertheless, the fracture behaviour is still rather brittle even at 750°C. TEM study of the material after the fatigue testing was performed. The dislocation activity is concentrated in the phase. The properties and behaviour of individual dislocations seem to be similar as those observed in single -phase TiAl alloys.