The purpose of this study is to predict the stability of slope using adaptive neuro fuzzy inference system (ANFIS). Based on limit equilibrium theory, four different methods of analyses, i.e. Morgenstern-Price, Janbu, Bishop and Ordinary were used to calculate the overall safety factor of various slope designs. Neuro-fuzzy inference system was used to map from a given input to an output. Important parameters such as height of slope (H), unit weight of soil (γ), angle of slope (θ), coefficient of cohesion (c) and internal angle of friction (ф) were used as the input parameters while overall safety factor was the output. ANFIS model to predict the stability of the slopes was generated from the calculated data. Results showed that factors of safety predicted using ANFIS agreed well with factors of safety calculated using Limit Equilibrium Methods (LEM).