Fabrication of βTCP with Fully-Interconnected Porous Structure
Calcium phosphate foam could be an ideal bone filler and scaffold for tissue engineering. This paper describes fabrication method of β-tricalcium phosphate (βTCP) foam with fully-interconnected porous structure by employing magnesium oxide (MgO) as βTCP stabilizer. The foam was prepared using the so-called ceramics foam method. MgO was added to calcium carbonate and dicalcium phosphate dihydrate so that 0, 1, 2, 3, 4, 6 and 8 mol% calcium would be substituted by magnesium (Mg) in βTCP structure. After sintering at 1500°C, crystal phase of the obtained foam included α-tricalcium phosphate (αTCP) when no Mg or less than 3 mol% Mg was added. In contrast, crystal phase was single phase βTCP when 3 mol% or higher Mg was added. The compressive strength was approximately 15 kPa and the porosity was above 95% for all specimens. No significant difference was observed between αTCP and βTCP foams in compressive strength and porosity when the sintering temperature was the same.
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
T. Nikaido et al., "Fabrication of βTCP with Fully-Interconnected Porous Structure", Key Engineering Materials, Vols. 493-494, pp. 135-138, 2012