The Effect of Pore Forming Agent Particle Size on the Porosity, Microstructure and In Vitro Studies of Hydroxyapatite Ceramics

Abstract:

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In situ viscous mass foaming with ammonium bicarbonate (NH4HCO3) as foaming agent was used for the preparation of porous hydroxyapatite ceramics. Three different particle fractions (100-300 μm, 300-500 μm, 500-1000 μm) of NH4HCO3 were used in order to evaluate the particle size effect on the ceramic microstructure. Foamed and dried green bodies were sintered at 1150°C. The porosity and microstructure of ceramics were determined with Archimedes method and scanning electron microscopy. As the NH4HCO3 particle fraction was decrease from 100-300 μm to 500-1000 μm, the open porosity increased from 42 to 54 %. In situ viscous mass foaming leads to the interconnected pore channels with wide pore size range (10-600 μm). In the present work cytotoxicity of obtained porous HA ceramics and fibroblast cell viability was investigated.

Info:

Periodical:

Key Engineering Materials (Volumes 493-494)

Main Theme:

Edited by:

Eyup Sabri Kayali, Gultekin Goller and Ipek Akin

Pages:

277-280

DOI:

10.4028/www.scientific.net/KEM.493-494.277

Citation:

V. Zalite et al., "The Effect of Pore Forming Agent Particle Size on the Porosity, Microstructure and In Vitro Studies of Hydroxyapatite Ceramics", Key Engineering Materials, Vols. 493-494, pp. 277-280, 2012

Online since:

October 2011

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Price:

$35.00

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