Bone Grafting Putty – Animal Experiments and Clinical Applications

Abstract:

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The aim of the described study was to generate and evaluate a putty-like bone graft substitute ready to use for dental and orthopedic surgery. According to the asking of clinicians the new material should avoid the necessity of mixing blood and bone graft during the surgical process. Therefor the granulous material NanoBone® has been combined with a hydrogel based on Polyvinylpyrrolidone (PVP) and tested in standardized rat tibia defect over a period of 12 weeks and evaluated histologically. The results showed no limitations of the granulate characteristics in matrix change and hence a high level of vascularization and bone formation. An example for dental application shows the outcome in the case of socket preservation.

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Periodical:

Key Engineering Materials (Volumes 529-530)

Main Theme:

Edited by:

Kunio Ishikawa and Yukihide Iwamoto

Pages:

285-290

Citation:

T. Gerber et al., "Bone Grafting Putty – Animal Experiments and Clinical Applications", Key Engineering Materials, Vols. 529-530, pp. 285-290, 2013

Online since:

November 2012

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$38.00

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