AP40 Bioactive Glass Ceramic by Sol-Gel Synthesis: In Vitro Dissolution and Cell-Mediated Bioresorption


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In this work, the sol-gel synthesis of AP40 bioactive glass system was reported. The obtained powder was fully characterised in terms of microstructure, composition and thermal behaviour by X-ray diffraction (XRD) measurements, Fourier transform infrared (FT-IR) spectroscopy, thermogravimetry and differential thermal analysis (TG-DTA). In vitro dissolution tests were performed in order to assess the degradation behaviour of sol-gel derived AP40 samples thermally treated at different temperatures. Finally, preliminary results on cytocompatibility are reported, based on bioresorption activity of human peripheral blood monocytes differentiated into osteoclasts on sintered disks.



Edited by:

Alessandra Bianco, Ilaria Cacciotti and Ilaria Cappelloni




I. Cacciotti et al., "AP40 Bioactive Glass Ceramic by Sol-Gel Synthesis: In Vitro Dissolution and Cell-Mediated Bioresorption", Key Engineering Materials, Vol. 541, pp. 41-50, 2013

Online since:

February 2013




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