Sensing Uric Acid with Bimetallic Nano Ag-Pt Particles
The emergence of nanoparticles (NPs) has opened new opportunities in analytical chemistry [. These NPs exhibit different properties and functionalities when compared to monometallic particles. In particular, they show enhanced selectivity and reactivity when used as catalysts and sensors [2-. The NPs have large surface area, high surface free energy, good biocompatibility and suitability, and it has been used in constructing electrochemical biosensors [7, . The fascinating physical and chemical properties of NPs offer excellent prospects for a wide range of bio sensing applications [ . Uric acid (UA) is the principal final product of purine metabolism in the human body [1. It has been shown that extreme abnormalities of UA levels are symptoms of several diseases (e.g. gout, hyper uricaemia and LeschNyhan syndrome)[11,1 .In general, electro active UA can be irreversibly oxidized in aqueous solution and the major product is allantoin [1. In continuation of our interest with the bimetal nanoparticle (BNP) sensing here in this study, we employed Ag/Pt BNPs for detecting of UA.
Evangelos Hristoforou and D.S. Vlachos
B. Karthikeyan and M. Murugavelu, "Sensing Uric Acid with Bimetallic Nano Ag-Pt Particles", Key Engineering Materials, Vol. 543, pp. 72-75, 2013