Preparation and Characterization of Tissue Engineering Scaffolds by Composite Molding of 3D Printing and Electrospinning
Currently, the developed electrospinning technique is capable of producing sub-micron diameter fibers, has better bionic of the extracellular matrix (ECM) on the size and morphology. Joining the nanofiber network into the porous macro scaffolds by the association of electrospinning with 3D printing technology can effectively support bionic microenvironment and improve the cell compatibility of scaffolds. We prepared the GE/CA-PCL scaffold by the composite approach, and characterized the morphology, cell compatibility and mechanical properties of scaffolds compared to the GE/CA scaffold prepared by single 3D printing technology. The composite molding process of 3D printing and electrospinning is a promising technique used for preparing scaffolds for tissue engineering and clinical medicine.
Y. M. Ma et al., "Preparation and Characterization of Tissue Engineering Scaffolds by Composite Molding of 3D Printing and Electrospinning", Key Engineering Materials, Vols. 645-646, pp. 1368-1373, 2015