Hydrothermal Processing for Increasing the Hydroxyl Ion Concentration in Hydroxyl Depleted Hydroxyapatite


Article Preview

Thermal spraying is commercially used to produce hydroxyapatite coatings, but the high temperature depletes hydroxyl ions in the structure. To return hydroxyapatite to its original state, it is necessary to restore the hydroxyl ion content in the structure. In this work, the effect of hydrothermal treatment on the hydroxyl ions was investigated in hydroxyapatite powder and thermally sprayed hydroxyapatite coatings. Samples were hydrothermally treated at 200 °C for 24 h and 48 h. Chemical phases were determined by X-ray diffraction, functional groups and hydroxyl ion concentration was examined by Fourier transform infra-red spectroscopy. Results showed that hydrothermal processing of hydroxyapatite coatings at 200 °C for 48 hours produced the greatest increase in the hydroxyl ion concentration by 29%.



Edited by:

Valdis Kokars




D. Ubele et al., "Hydrothermal Processing for Increasing the Hydroxyl Ion Concentration in Hydroxyl Depleted Hydroxyapatite", Key Engineering Materials, Vol. 762, pp. 42-47, 2018

Online since:

February 2018




* - Corresponding Author

[1] J. Kolmas, S. Krukowski, A. Laskus, M. Jurkitewicz, Synthetic hydroxyapatite in pharmaceutical applications, Ceramics International 42 (2016) 2472-2487.

DOI: https://doi.org/10.1016/j.ceramint.2015.10.048

[2] S.V. Dorozhkin, Calcium orthophosphate bioceramics, Ceramics International 41 (2015) 13913-13966.

DOI: https://doi.org/10.1016/j.ceramint.2015.08.004

[3] R. Narayanan, S.K. Seshadri, T.Y. Kwon, K.H. Kim, Review: Calcium Phosphate-Based Coatings on Titanium and Its Alloys, J. Biomed. Mater. Res. 85B (2008) 279-299.

DOI: https://doi.org/10.1002/jbm.b.30932

[4] Y. Cao, J. Weng, J. Chen, J. Feng, Z. Yang, X. Zhang, Water vapour-treated hydroxyapatite coatings after plasma spraying and their characteristics, Biomaterials 17 (1996) 419-424.

DOI: https://doi.org/10.1016/0142-9612(96)89658-x

[5] I. Demnati, M. Parco, D. Grossin, I. Fagoaga, C. Drouet, G. Barykin, C. Combes, I. Braceras, S. Goncalves, C. Rey, Hydroxyapatite coating on titanium by a low energy plasma spraying mini-gun, Surface & Coatings Technology 206 (2012) 2346-2353.

DOI: https://doi.org/10.1016/j.surfcoat.2011.10.025

[6] C.W. Yang, T.S. Lui, T.M. Lee, E. Chang, Effect of Hydrothermal Treatment on Microstructural Feature and Bonding Strength of Plasma-Sprayed Hydroxyapatite on Ti-6Al-4V, Materials Transactions 45 (2004) 2922-2929.

DOI: https://doi.org/10.2320/matertrans.45.2922

[7] L. Pluduma, Hydroxyl Ion Quantification in Hydroxyapatite and the Effect on the Biological Response, PhD Thesis, Riga: [RTU], (2017) 134 p.

[8] J.C. Eliott, Structure and Chemistry of the Apatites and Other Calcium Orthophosphates, Volume 18, first ed., Elsevier, London, (1994).

[9] K.A. Gross, D. Muller, H. Lucas, D.R. Haynes, Osteoclast resorption of thermal spray hydoxyapatite coatings is influenced by surface topography, Acta Biomaterialia 8 (2012) 1948-(1956).

DOI: https://doi.org/10.1016/j.actbio.2012.01.023

[10] C. Rey, C. Combes, C. Drouet, A. Lebugle, H. Sfihi, A. Barroug, Nanocrystalline apatites in biological systems: characterisation, structure and properties, Mat. -wiss. u. Werkstofftech 38 (2007) 996-1002.

DOI: https://doi.org/10.1002/mawe.200700229

[11] A. Kaflak, W. Kolodziejski, Complementary information on water and hydroxyl groups in nanocrystalline carbonated hydroxyapatites from TGA, NMR and IR measurements, Journal of Molecular Structure 990 (2011) 263-270.

DOI: https://doi.org/10.1016/j.molstruc.2011.01.056

[12] C. Rey, C. Combes, C. Drouet, H. Sfihi, A. Barroug, Physico-chemical properties of nanocrystalline apatites: Implications for biominerals and biomaterials, Materials Science and Engineering C 27 (2007) 198-205.

DOI: https://doi.org/10.1016/j.msec.2006.05.015

[13] N. Vandecandelaere, C. Rey, C. Drouet, Biomimetic apatite-based biomaterials: on the critical impact of synthesis and post-synthesis parameters, J Mater Sci: Mater Med 23 (2012) 2593-2606.

DOI: https://doi.org/10.1007/s10856-012-4719-y

[14] S. Koutsopoulos, Synthesis and characterization of hydroxyapatite crystals: A review study on the analytical methods, J Biomed Mater Res. 62 (2002) 600-612.

DOI: https://doi.org/10.1002/jbm.10280