Fabrication of SiO2-Coated Magnetic Nanoparticles for Applications to Protein Separation and Purification


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Coating of -Fe2O3 nanoparticles with SiO2 layer by wet chemical synthesis and its applications to protein separation and purification were investigated. The average particle size of -Fe2O3 core was 20 nm and SiO2 layer thickness was 5 nm. The band of OH- radicals on SiO2 layer was detected between 3600 and 3200 cm-1 in wave numbers, which showed that the surface property of coated nanoparticles was similar to that of conventional fumed silica. Finally, the feasibility of -Fe2O3/SiO2 nanoparticles for magnetic separation media in various bio processes was discussed in terms of structural and functional properties such as pore structure and magnetic properties.



Materials Science Forum (Volumes 449-452)

Edited by:

S.-G. Kang and T. Kobayashi




S.H. Yun et al., "Fabrication of SiO2-Coated Magnetic Nanoparticles for Applications to Protein Separation and Purification", Materials Science Forum, Vols. 449-452, pp. 1033-1036, 2004

Online since:

March 2004




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