Processing and Mechanical Properties of Biphasic Calcium-Phosphate/Poly-L-Lactide Composite Biomaterials


Article Preview

This study descripts processing of biphasic calcium-phosphate (BCP) and poly-L-lactide (PLLA) biocomposite implant material. The composite was obtained by mixing completely dissolved PLLA with granules of high crystalline BCP and was compacted by hot pressing using cylindrical dies at 450 K temperature and 98.1 MPa pressure, for 30 and 60 minutes. Wide-angle Xray structural (WAXS) analyses of BCP, PLLA and BCP/PLLA composite blocks were made followed by calorimetric (DSC) tests in the 320-520 K temperature range. Compression tests revealed that Young’s modulus and compressive strength of the composite increased with extended hot pressing time and were found to be within the bounds of the cortical bone values.



Materials Science Forum (Volumes 471-472)

Edited by:

Xing Ai, Jianfeng Li and Chuanzhen Huang




C. Y. Tang et al., "Processing and Mechanical Properties of Biphasic Calcium-Phosphate/Poly-L-Lactide Composite Biomaterials", Materials Science Forum, Vols. 471-472, pp. 273-277, 2004

Online since:

December 2004




[1] O. Gauthier, J. M. Bouler, E. Aguado, et al: J. Mater. Sci.: Mater. Med. Vol. 10 (1999), p.199.

[2] F.H. Lin, C.J. Liao, K.S. Chen, et al: J. Biomed. Mater. Res. Vol. 51 (2000), p.157.

[3] O.E. Petrov, E. Dyulgerova, L. Petrov, et al: Mater. Lett. Vol. 48 (2001), p.162.

[4] C.C.P.M. Verheyen, J.R. de Wijn, C.A. van Blitterswijk, et al: J. Biomed. Mater. Res. Vol. 26 (1992), p.1277.

[5] N. Ignjatovic, S. Tomic, M. Dakic, et al: Biomaterials Vol. 20 (1999), p.809.

[6] N. Ignjatovic, V. Savic, S. Najman, et al: Biomaterials Vol. 22 (2001), p.571.

[7] Y. Shikinami and M. Okuno: Biomaterials Vol. 20 (1999), p.859.

[8] N.C. Bleach, S.N. Nazhat, K.E. Tanner, et al: Biomaterials Vol. 23 (2002), p.1579.

[9] Joint Committee on Powder Diffraction Standards, 1600 Park Lane, Swarthmore, PA 19081, USA.

[10] C.K. Hsu: Mater. Chem. Phys. Vol. 80 (2003), p.409.

[11] E.I. Dorozhkina and S.V. Dorozhkin: Chem. Mater. Vol. 14 (2002), p.4267.

[12] S. Gogolewski, J. Mainil-Varlet and J. Dillan: J. Biomed. Mater. Res. Vol. 32 (1996), p.227.

[13] Y. Jin-San, O. Sung-Hwan, K. Mal-Nam, et al: Polymer Vol. 40 (1999), p.2303.