Compare of Electrospinning PLA and PLA/β-TCP Scaffold in Vitro
In recent years, electrospinning process is gradually applied in producing tissue-engineering scaffold. In this study, we chose polylacticacid(PLA) and β-tertiary calcium phosphate(β-TCP) as raw materials to fabricate PLA/β-TCP biodegradable composite scaffold by electrospinning process. The characteristics of the scaffold and effect of the scaffolds to cell proliferation and cell adhesion was studied. Compare with pure PLA scaffold, blendingβ-TCP in the spinning process of the scaffold could improve the properties of the scaffold, especially the hydrophilicity and the proliferation and adhesion of cells, this means that the material is more potential to be used as tissue engineering scaffolds.
Z.Y. Zhong, H. Saka, T.H. Kim, E.A. Holm, Y.F. Han and X.S. Xie
H. S. Fan et al., "Compare of Electrospinning PLA and PLA/β-TCP Scaffold in Vitro", Materials Science Forum, Vols. 475-479, pp. 2379-2382, 2005