Study on Adhesion and Biocompatibility of Copolymer of MMA-BMA-MAA for Coronary Stents Coatings

Abstract:

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Implantation of drug releasing coronary stents has been developed as an useful method for prevention of the restenosis in blood vessels. Copolymers of methyl methacrylate (MMA), butyl methacrylate (BMA) and methacrylic acid (MAA) were prepared as the coating polymer for drug releasing stent. The adhesion of the polymer with metal substrate and the biocompatibility were studied. Effect of the polymer composition on the adhesion between polymer coatings and metal substrate, as well as the effect of the polymer purification method on biocompatibility of the polymer, was studied. The results showed that the copolymer coating has good dry and wet adhesion properties, which can be improved by control of the polymer compositions. Biocompatibility of the prepared copolymer comes within the permission limit.

Info:

Periodical:

Materials Science Forum (Volumes 475-479)

Main Theme:

Edited by:

Z.Y. Zhong, H. Saka, T.H. Kim, E.A. Holm, Y.F. Han and X.S. Xie

Pages:

2395-2398

DOI:

10.4028/www.scientific.net/MSF.475-479.2395

Citation:

L.-L. Tan et al., "Study on Adhesion and Biocompatibility of Copolymer of MMA-BMA-MAA for Coronary Stents Coatings", Materials Science Forum, Vols. 475-479, pp. 2395-2398, 2005

Online since:

January 2005

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$35.00

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