The Transfection Efficacy of Chitosan-DNA Nanoparticles on MGC803, SMMC-7721, MG63 Cells

Abstract:

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Chitosan-DNA nanoparticles were synthesized from the complexation of chitosan solution and the plasmid pCD-GFP encoding green fluorescent protein through a coacervation process. The nanoparticles formed were of diameter inferior to 100 nm. The transfection efficacy of chitosan-DNA nanoparticles in MGC803 cells was higher than in SMMC-7721 cells, whereas the plasmid GFP was not expressed in MG63 cells.

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Periodical:

Materials Science Forum (Volumes 510-511)

Edited by:

Hyung Sun Kim, Yu Bao Li and Soo Wohn Lee

Pages:

382-385

Citation:

S. Chen et al., "The Transfection Efficacy of Chitosan-DNA Nanoparticles on MGC803, SMMC-7721, MG63 Cells", Materials Science Forum, Vols. 510-511, pp. 382-385, 2006

Online since:

March 2006

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$38.00

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DOI: https://doi.org/10.1016/s0142-9612(02)00507-0