Obtention of TCP Porous Ceramic Using Albumin
In the last years, the porosity in ceramic materials for implants production has motivated the development of various technologies. Calcium phosphate ceramics, in special the tricalcium phosphate - TCP, are very promising as bone substitutes and scaffolds for tissue engineering. The macroporosity incorporation in TCP ceramics by porogenic, foaming and consolidator agent, as globular protein (ovalbumin) was the focus of this work. Preliminary studies of zeta potential were made to have a suitable suspension. Ovalbumin amounts (5-7 wt%) were added to the ceramic slurries and suspensions with a solid percentage higher than 60 wt% were obtained. The interaction albumin/surfactant with detergency properties was evaluated by pH and viscosity measurements. The foam was produced by mechanical stirring. The results suggested that the presence of the surfactant increase the volume and stability of foam. After drying, burnout and sintering (1200oC/30 min.) the phase composition of the foams was determined by X-ray diffraction. The microstructure and porosity were evaluated by scanning electron microscopy. SEM micrographs of the foam show that the structure consists of a permeable porous network, being observed spherical and interconnected pores.
Lucio Salgado and Francisco Ambrozio Filho
C. Ribeiro et al., "Obtention of TCP Porous Ceramic Using Albumin", Materials Science Forum, Vols. 530-531, pp. 587-592, 2006