In the process of global economy development and competition, how to strengthen the cooperation of enterprises in the supply chain environment plays a very important role to the success of enterprises. As well known, the IT technology is one of the quite essential factors to provide quicker and more accurate information for the enterprises, and therefore enhance the enterprises’ operation efficiency. In order to adapt to the supply chain (SC) environment and support for other enterprises’ common development in SC, we have to develop more powerful and unified IT technology. What is elaborated in this paper is the framework of the information cooperation system which is SC oriented. It does not deny or overthrow the legacy applications of enterprises, but to put forward a framework based on the old applications in SC. It also unifies the Web Service and references the principles of VPN. We call it the framework of Virtual Private Supply Chain Management (VPSCM). The principle, the model and the use of VPSCM as well as some other related issues are going to be explained in this paper.