Accurately material constitutive model is essential to understand and predict machining process. High temperature split Hopkinson pressure bar (SHPB) test system is used to investigate flow stress behavior and characteristics of 7050-T7451 aluminum alloy. Specimens are tested from 200°C to 550°C at intervals of 50°C and room temperature, at strain-rate of 2800s-1. The experimental results show that flow stress is strongly dependent on temperature as well as strain rate, flow stress decreases with the increase of temperature, while increase with the increasing of strain rate. The material parameters are determined for both Johnson-Cook constitutive equation and modified Johnson-Cook constitutive equation. The modified JC equation is more suitable for expressing the dynamic behavior of 7050-T7451 aluminum alloy.