Fabrication of Fiber-Reinforced CPC Composite Artificial Bone by RP/RT

Abstract:

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Self-hardening calcium phosphate cement (CPC) could not be used to repair a large segmental defect in a load-bearing bone because of its brittleness and weak shock resistance as well as ultra-minute pores. Recent studies incorporated fibers into CPC to improve its strength. A novel approach by rapid prototyping and rapid tool technique (RP/RT) was used in this paper to fabricate fibre-reinforced CPC composite artificial bone. The subsequent mechanical experiments demonstrated that the compressive strength of the CPC-fiber artificial bone was 24MPa, which was significantly higher than 6MPa for CPC control without fiber. And in-vivo experiment about canine radius repair proved that the implanted CPC-fiber artificial bone enabled to provide short-time reinforced mechanical strength, while the degraded fibers created new macropores for new tissue ingrowth. In summary, the CPC-fiber artificial bone may facilitate bone ingrowth and its four times increase in strength may help extend the use of CPC to larger bone repairs in moderately stress-bearing locations.

Info:

Periodical:

Materials Science Forum (Volumes 532-533)

Edited by:

Chengyu Jiang, Geng Liu, Dinghua Zhang and Xipeng Xu

Pages:

745-748

Citation:

Q. Lian et al., "Fabrication of Fiber-Reinforced CPC Composite Artificial Bone by RP/RT", Materials Science Forum, Vols. 532-533, pp. 745-748, 2006

Online since:

December 2006

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$38.00

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DOI: https://doi.org/10.1016/s8756-3282(99)00130-1

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