Electrochemical Influence of Collagen Piezoelectric Effect in Bone Healing


Article Preview

Bone healing and growth are controlled by the rate of deposition of hidroxiapatite (HA). This process have been so far accredited to the work of osteoblasts, which are attracted by the electrical dipoles produced either by piezoelectricity, due to deformation of the bone, specially the collagen in it, or due to outside electrical stimuli. The present work shows that even without osteoblasts present, the piezoelectric dipoles produced by deformed collagen, can produce the precipitation of HA by electrochemical means, without catalyzer as in biomimetic deposition. These findings could clarify the contribution of osteoblasts in bone growth as compared to the electrochemical action by itself. Further studies ascertaining the osteoblastic activity due to the electric field are being advanced.



Materials Science Forum (Volumes 544-545)

Edited by:

Hyungsun Kim, Junichi Hojo and Soo Wohn Lee




K. Noris-Suárez et al., "Electrochemical Influence of Collagen Piezoelectric Effect in Bone Healing", Materials Science Forum, Vols. 544-545, pp. 981-984, 2007

Online since:

May 2007




[1] A.A. Marino, R.O. Becker. Nature, Vol 228 (1975) p.627.

[2] L. Knott, A.J. Bailey. Bone vol. 22 No. 3 (1998) p.181.

[3] C.C. Silva, D. Thomazini, AG. Pinheiro, N. Aranha, S.D. Figueiro, J.C. Goes, A.S.B. Sombra, Mater. Sci. Eng., Vol B86, (2001), p.210.

[4] K. Noris-Suarez, M. Romanello, P. Bettica, L. Moro, Calcif. Tissue Int., Vol 58, (1996) pp.65-69.

[5] Y. Ebisawa, T., Kokubo, K. Ohura, T. Yamamuro, J Mater Sci Mater Medicine Vol 1 (1990) p.239.

[6] K. Noris-Suárez, I. Barrios de Arenas, M. Vasquez, Y. Baron, I. Atias, J. Bermúdez, C. Morillo, Y. Olivares, J. Lira. Rev. Latin. Am. Met. Mat., Vol. 23 (2005), p.82.