Titanium, zirconium and magnesium alloys are considered to be biocompatible, and can be used as implants such as hip ball and sockets and to make medical equipments. Biomaterials with hybrid structures in some applications utilizing the beneficial properties of different metals together are considered potential implant materials. Therefore, in this study, experimental trials were attempted to bond pure magnesium, AM60 (6 wt% Al-0.27 wt% Mn), and AZ31 (3 wt% Al-1 wt% Zn) alloys to pure zirconium and Ti6Al4V (6 wt% Al-4 wt% V) alloy to experimentally evaluate the forming bimetallic structures by diffusion bonding technique by vacuum hot pressing. SEM analysis showed the presence of a significant diffusion zone and a presence of diffusion bonding in some metallic couples. It may be suggested that novel hybrid implant materials, composed of diffusion couples of magnesium, zirconium and titanium alloys may emerge in the future.