In this paper, the process is divided into two steps. (1) First, the ceramic die used to fabricate the denture base was made by mixing the green of ZrO2 and TiO2 with PVA and press them into the oral cavity model to get the ceramic die before sintered. Then it was sintered to be the ceramic die after sintered in the atmosphere. (2) Second, the 0.8mm Ti-6Al-4V plate covered with BN was fabricated to be denture base by blow forming at the optimal superplastic forming temperature using nitrogen gas. The pattern of the Ti6Al4V denture base was the same as the detail of the ceramic die.(3) Third, the thickness of Ti-6Al-4V alloy denture base was investigated and the accuracy was measured by compared the distance between the marked points of the framework against the ceramic die. Although the thickness of denture base was reduced by superplastic forming, the framework had about 78.5% of the original plate thickness. Differences in the thickness did not significantly affect the gap discrepancy and the accuracy of fit of the denture base would satisfy ordinary clinical requirements.