Surface Modification of Hydrogels and Cell Adhesion


Article Preview

Polymer hydrogels have many different functions in the field of tissue engineering and medicine. Modification of 2-hydroxy-ethyl-methacrylate (HEMA) and 2-ethyl-oxy-ethylmethacrylate (EOEMA) by plasma treatment performed in Ar atmosphere at RT for 0-400 s was studied using different techniques. Sample ablation was determined by gravimetry, surface wettability and aging by goniometry, chemical structure by FTIR spectroscopy and surface morphology by AFM microscopy. The plasma modification changes the sample surface morphology. In vitro cultivation shows that the plasma treatment changes the proliferation of human LEP cells.



Materials Science Forum (Volumes 567-568)

Edited by:

Pavel Šandera




K. Kolářová et al., "Surface Modification of Hydrogels and Cell Adhesion", Materials Science Forum, Vols. 567-568, pp. 265-268, 2008

Online since:

December 2007




[1] R. Bechera, H.M. Kopperuda and R.H. Ala, Dental Mater. Vol. 22 (2006), p.630.

[2] L. Grossterlindena, A. Janssena and N. Schmitza, Biomaterials Vol. 27 (2006), p.3379.

[3] A. S. Hoffman, A Drug Delivery Rev. Vol. 43 (2002), p.3.

[4] B. Dvořánková, K. Smetana Jr., R. Königová, H. Singerová, J. Vacík, M. Jelínková, Z. Kapounková and M. Zahradník, Biomaterials Vol. 19 (1998), p.141.

[5] D. M. Choi , C. K. Park and C. P. Park, Polymer Vol. 25 (1997), p.6243.

[6] V. Švorčík, K. Kolářová, P. Slepička, A. Macková, M. Novotná and V. Hnatowicz, Polym. Degr. Stab. Vol. 91 (2006), p.1219.

[7] V. Švorčík, K. Kolářová, B. Dvořánková and J. Michálek, Rad. Eff. Def. Sol. Vol. 161 (2006), p.15.

[8] D. Hegemann, H. Brunner and Ch. Onehr, Nucl. Instrum. Meth Vol. B208 (2003), p.281.

[9] P. K. Chu, J. Y. Chen, L.P. Wang and N. Huang, Mater. Sci. Eng. Vol. 36 (2002), p.143.

[10] C. M. Chan, T. M. Ko and H. Hiraoka, Surf. Sci. Rep. 24 (1996), p.1.

[11] K. Ročková, V. Švorčík, L. Bačáková, B. Dvořánková and V. Hnatowicz, Nucl. Instrum. Meth. Vol. B225 (2004), p.275.

[12] V. Švorčík, V. Kotál, O. Bláhová, M. Špírková, P. Sajdl and V. Hnatowicz, Nucl. Instrum. Meth. B Vol. 224 (2006), p.365.

[13] K.S. Kim, Ch.M. Ryu, Ch.S. Park G.S. Sur and Ch.E. Park, Polymer Vol. 44 (2003), p.6287.

Fetching data from Crossref.
This may take some time to load.