Preliminary Studies Regarding the Behaviour of New Titanium Implants
This paper presents a study concerning a new titanium-based product reached by the specific techniques of powder metallurgy. The product was tested in vitro to corrosion in artificial saliva and in vivo by biological inocuity on sheep and rats for biocompatibility. The chemical composition of artificial saliva solutions used for general corrosion tests were: Fusayama solution; Carter solution; Ericsson solution; Hank solution; Ringer solution. The exposure length was 48, 720, 1440 and 2784 hours. On the sheep, six titanium implants of purity 99.89%, sintered with microporosities and nanoporosities at the surface were administered. Function of implant location, three cm incisions in the skin was made in the following regions: retroscapular for subcutaneous implants, in the tibial diaphysis for the subperiostal implant and in the Latimus Dorsi region for the intramuscular implant. Three different lots of Wistar breed rats were used; the sintered 3.5/1.5 cm titanium implants were placed subcutaneously and intermuscles. Parameters of descriptive statistics were used to assess inflammatory reaction.
Ionel Chicinaş and Liviu Brânduşan
C. R. Roman and L. A. Sorcoi, "Preliminary Studies Regarding the Behaviour of New Titanium Implants", Materials Science Forum, Vol. 672, pp. 233-236, 2011