Osteoblast Behaviour on Nanostructured Ti-Bioceramic Composites


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Ti and Ti-based alloys are preferred materials in the production of implants in both medical and dental applications. One of the methods that allow the change of biological properties of Ti alloys is the modification of their chemical composition and microstructure. In this study, new biocompatible, nanostructured Ti-x vol% SiO2, Ti-x vol% 45S5 Bioglass, and Ti-x vol% HAp (x=0, 3, 10) materials have been developed, manufactured and studied in terms of their biocompatibility. These materials give the possibility of controlling in detail the grain structure and the composition of the alloy and, consequently, the mechanical and biocompatibility performances. Our results of in vitro studies show that these bionanocomposites have excellent biocompatibility and could integrate with bone. After 1st day of incubation cells show good adhesion to the surface of studied samples in the form of filopodia. After 5 days of incubation, the typical monolayer was observed. With regard to microcrystalline Ti it could help to obtain better dental implants with better mechanical properties and corrosion resistance.



Edited by:

Maria Richert




K. Jurczyk et al., "Osteoblast Behaviour on Nanostructured Ti-Bioceramic Composites", Materials Science Forum, Vol. 674, pp. 153-158, 2011

Online since:

February 2011




[1] R.Z. Valiev, I.P. Semenova, V.V. Latysh, H. Rack, T.C. Lowe, J. Petruzelka, L. Dluhos, D. Hrusak and J. Sochova: Adv. Eng. Mater. Vol. 10 (2008), p.1.

DOI: https://doi.org/10.1002/adem.200800026

[2] J. Jakubowicz, K. Jurczyk, K. Niespodziana and M. Jurczyk: Electrochem. Commun. Vol. 11 (2009), p.461.

[3] X. Liu, P.K. Chub and C. Ding: Mat. Sc. Eng. R Vol. 47 (2004), p.49.

[4] H.J. Rack and J.J. Qazi: Mater. Sci. Eng. C Vol. 26 (2006), p.1269.

[5] B.C. Ward and T.J. Webster: Mat. Sc. Eng. C Vol. 27 (2007), p.575.

[6] K. Niespodziana, K. Jurczyk, J. Jakubowicz and M. Jurczyk: Mat. Chem. Phys. Vol. 123 (2010), p.160.

[7] K. Niespodziana, K. Jurczyk and M. Jurczyk: Archives Metall. Mater. Vol. 53 (2008), p.875.

[8] A. Yamamoto, Y. Kohyama, D. Kuroda and T. Hanawa: Mat. Sc. Eng. C Vol. 24 (2004), p.737.

[9] T.J. Webster and J.U. Ejiofor: Biomaterials Vol. 25 (2004), p.4731.

[10] C. Suryanarayna: Progr. Mater. Sc. Vol. 46 (2001), p.1.

[11] J.R. Groza: NanoStructured Mater. Vol. 12 (1999), p.987.

[12] C.Q. Ning and Y. Zhou: Biomaterials Vol. 23 (2002), p.2909.

[13] B.C. Ward and T.J. Webster: Biomaterials Vol. 27 (2006), p.3064.