Finite Element Modelling for Internal Bionic Architecture Optimization of Artificial Human Bones

Abstract:

Article Preview

Clinical medicine shows that the scaffold of artificial human bone must have a certain porosity, good connectivity and adequate mechanical strength. Controlled porosity, pore size, shape and interconnectivity of the scaffold heavily influence the structural strength, transport properties, and the micro-environment for cells and tissue in-growth. In this paper, finite element analysis software was used. A micro-porous unit with mechanical properties similar to the natural bone was produced. Then the interconnected scaffold of tissue with a specific porosity and gradient pore was built according to the optimized micro-porous unit. It was confirmed that the porosity and elastic modulus of the mold were within the bounds of human bone. Analysis using ADINA8.3 ensured that the mold had satisfactory mechanical properties of bone. Finally, STL files were generated by the software and the mold was manufactured using SLS.

Info:

Periodical:

Edited by:

Enhou Han, Guanghong Lu and Xiaolin Shu

Pages:

95-101

DOI:

10.4028/www.scientific.net/MSF.689.95

Citation:

L. J. Yang et al., "Finite Element Modelling for Internal Bionic Architecture Optimization of Artificial Human Bones", Materials Science Forum, Vol. 689, pp. 95-101, 2011

Online since:

June 2011

Export:

Price:

$38.00

[1] R. Langer and J.P. Vacanti: Tissue engineering, Science 260 (1993), p.920–926.

[2] J. Zeltinger, J.K. Sherwood, D.A. Graham, R. Mueller and L.G. Griffith: Tissue Eng 7 (2001), p.557–572.

[3] Chen Zhongzhong and Li Dichen: Journal of Mechanical Engineering, Vol. 39 (2003): p.144~148. (in Chinese).

[4] Cai Shengyong and Xi Juntong: Journal of Mechanical Engineering, Vol. 45 (2009), pp.297-304. (in Chinese).

[5] Pallavi Lal and Wei Sun: Computer-Aided Design, Vol. 36 (2004), pp.487-497.

[6] B. Starly and W. Lau: Computer-Aided Design, Vol. 38 (2005), pp.115-124.

[7] Wang Yingjian: Advances in Mechanics, Vol. 26 (1996), pp.416-423.

[8] Feng Yuanzhen: Biomechanics (Science Press, China1983).

[9] Jin Yan: Principles and techniques of tissue engineering (The Fourth Military Medical University Press, China 2004).

[10] Zeng Zhengming: Material Handbook of Mechanical Engineering (China Machine Press, China 2005).

In order to see related information, you need to Login.