Effects of Grain Size and Texture on the Biocompatibility of Commercially Pure Titanium


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Ultra fine grained (UFG) pure titanium fabricated by severe plastic deformation techniques has been recently considered for biomedical applications. In this study, the effects of grain size and crystallographic orientation on the biocompatibility of commercially pure titanium have been evaluated. Samples having significant differences in terms of average grain size (from 0.4 to 20 mm) and crystallographic textures have been produced using equal channel angular pressing (ECAP) and compared. X-ray diffraction and electron back scattered diffraction (EBSD) were used to document the texture and microstructural properties. Cell attachment tests were done to study the biocompatibility of the samples using MC3T3 pre-osteoblast cells. The number of attached cells was found to be higher on the samples having more (0002) plane parallel to the surface regardless of their grain sizes. It was concluded that the texture plays a more significant role than the grain size in the biocompatibility of pure titanium.



Materials Science Forum (Volumes 702-703)

Edited by:

Asim Tewari, Satyam Suwas, Dinesh Srivastava, Indradev Samajdar and Arunansu Haldar






M. Hoseini et al., "Effects of Grain Size and Texture on the Biocompatibility of Commercially Pure Titanium", Materials Science Forum, Vols. 702-703, pp. 822-825, 2012

Online since:

December 2011




[1] R.Z. Valiev and T.G. Langdon, Progress in Materials Science, 51 (2006) 881-981.

[2] Y. Estrin, et al., Journal of Biomedical Materials Research Part A, 90A (2009) 1239-1242.

[3] S. Faghihi, et al., Biomaterials, 28 (2007) 3887-3895.

[4] S. Faghihi, et al., Advanced Materials, 19 (2007) 1069-1073.

[5] V. Truong, et al., Applied Microbiology and Biotechnology, 83 (2009) 925-937.

[6] R.Z. Valiev, et al., Advanced Engineering Materials, 10 (2008) B15-B17.

[7] M. Hoseini, et al., Corrosion Science, 51 (2009) 3064-3067.

[8] L. Addadi and S. Weiner, Proceedings of the National Academy of Sciences, 82 (1985) 4110-4114.

[9] S. Faghihi, et al., Biomaterials, 27 (2006) 3532-3539.

[10] E. Zimmerman, L. Addadi, and B. Geiger, Journal of Structural Biology, 125 (1999) 25-38.

[11] M. Hoseini, et al., Materials Characterization, 61 (2010) 1371-1378.

[12] I. Alexandrov, et al., Metals and Materials International, 9 (2003) 151-156.

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