Biocompatible Ceramic-Biopolymer Coatings Obtained by Electrophoretic Deposition on Electron Beam Structured Titanium Alloy Surfaces

Abstract:

Article Preview

An area of major interest in biomedical engineering is currently the development of improved materials for medical implants. Research efforts are being focused on the investigation of surface modification methods for metallic prostheses due to the fundamental bioinert character of these materials and the possible ion release from their surfaces, which could potentially induce the interfacial loosening of devices after implantation. Electron beam (EB) structuring is a novel technique to control the surface topography in metals. Electrophoretic deposition (EPD) offers the feasibility to deposit at room temperature a variety of materials on conductive substrates from colloidal suspensions under electric fields. In this work single layers of chitosan composite coatings containing titania nanoparticles (n-TiO2) were deposit by EPD on electron beam (EB) structured Ti6Al4V titanium alloy. Surface structures were designed following different criteria in order to develop specific topography on the Ti6Al4V substrate. n-TiO2 particles were used as a model particle in order to demonstrate the versatility of the proposed technique for achieving homogenous chitosan based coatings on structured surfaces. A linear relation between EPD time and deposition yield on different patterned Ti6Al4V surfaces was determined under constant voltage conditions, obtaining homogeneous EPD coatings which replicate the 3D structure (pattern) of the substrate surface. The present results show that a combination of both techniques can be considered a promising surface modification approach for metallic implants, which should lead to improved interaction between the implant surface and the biological environment for orthopaedic applications.

Info:

Periodical:

Main Theme:

Edited by:

C. Sommitsch, M. Ionescu, B. Mishra, E. Kozeschnik and T. Chandra

Pages:

1552-1557

Citation:

C. Ramskogler et al., "Biocompatible Ceramic-Biopolymer Coatings Obtained by Electrophoretic Deposition on Electron Beam Structured Titanium Alloy Surfaces", Materials Science Forum, Vol. 879, pp. 1552-1557, 2017

Online since:

November 2016

Export:

Price:

$38.00

* - Corresponding Author

[1] M. Niinomi, Mechanical properties of biomedical titanium alloys, Mater. Sci. Eng. A, vol. 243, no. 1–2, p.231–236, Mar. (1998).

[2] H. J. Rack and J. I. Qazi, Titanium alloys for biomedical applications, Mater. Sci. Eng. C, vol. 26, no. 8, p.1269–1277, Sep. (2006).

[3] M. Geetha, a. K. Singh, R. Asokamani, and a. K. Gogia, Ti based biomaterials, the ultimate choice for orthopaedic implants – A review, Prog. Mater. Sci., vol. 54, no. 3, p.397–425, May (2009).

DOI: https://doi.org/10.1016/j.pmatsci.2008.06.004

[4] W. Ho, C. Ju, and J. Chern Lin, Structure and properties of cast binary Ti–Mo alloys, Biomaterials, vol. 20, no. 22, p.2115–2122, Nov. (1999).

DOI: https://doi.org/10.1016/s0142-9612(99)00114-3

[5] R. G. Flemming, C. J. Murphy, G. a Abrams, S. L. Goodman, and P. F. Nealey, Effects of synthetic micro- and nano-structured surfaces on cell behavior., Biomaterials, vol. 20, no. 6, p.573–88, Mar. (1999).

DOI: https://doi.org/10.1016/s0142-9612(98)00209-9

[6] J. -P. Kaiser, A. Reinmann, and A. Bruinink, The effect of topographic characteristics on cell migration velocity., Biomaterials, vol. 27, no. 30, p.5230–41, Oct. (2006).

DOI: https://doi.org/10.1016/j.biomaterials.2006.06.002

[7] Curtis and C. Wilkinson, Topographical control of cells., Biomaterials, vol. 18, no. 24, p.1573–83, Dec. (1997).

[8] M. J. Santillán, N. E. Quaranta, and a. R. Boccaccini, Titania and titania-silver nanocomposite coatings grown by electrophoretic deposition from aqueous suspensions, Surf. Coatings Technol., vol. 205, no. 7, p.2562–2571, (2010).

DOI: https://doi.org/10.1016/j.surfcoat.2010.10.001

[9] P. Shi, W. F. Ng, M. H. Wong, and F. T. Cheng, Improvement of corrosion resistance of pure magnesium in Hanks' solution by microarc oxidation with sol-gel TiO2 sealing, J. Alloys Compd., vol. 469, no. 1–2, p.286–292, (2009).

DOI: https://doi.org/10.1016/j.jallcom.2008.01.102

[10] L. -H. Li, Y. -M. Kong, H. -W. Kim, Y. -W. Kim, H. -E. Kim, S. -J. Heo, and J. -Y. Koak, Improved biological performance of Ti implants due to surface modification by micro-arc oxidation, Biomaterials, vol. 25, no. 14, p.2867–2875, (2004).

DOI: https://doi.org/10.1016/j.biomaterials.2003.09.048

[11] R. Tomaszek, L. Pawlowski, L. Gengembre, J. Laureyns, and A. Le Maguer, Microstructure of suspension plasma sprayed multilayer coatings of hydroxyapatite and titanium oxide, Surf. Coatings Technol., vol. 201, p.7432–7440, (2007).

DOI: https://doi.org/10.1016/j.surfcoat.2007.02.013

[12] D. L. Cochran, R. K. Schenk, a. Lussi, F. L. Higginbottom, and D. Buser, Bone response to unloaded and loaded titanium implants with a sandblasted and acid-etched surface: A histometric study in the canine mandible, J. Biomed. Mater. Res., vol. 40, no. 1, p.1–11, (1998).

DOI: https://doi.org/10.1002/(sici)1097-4636(199804)40:1<1::aid-jbm1>3.0.co;2-q

[13] B. G. I. Dance, and A.L. Buxton An Introduction to Surfi-Sculpt® Technology-New Opportunities, New Challenges, In Proceedings of the 7th International Conference on Beam Technology, pp.75-84, (2007).

[14] C. Ramskogler, S. Mostofi, F. Warchomicka, A. Weinberg, and C. Sommitsch, Surface structuring by electron beam technique in titanium grade 2 and Ti6Al4V for biomedical application, In Proceedings of the 13th World Conference on Titanium, (2015).

DOI: https://doi.org/10.1002/9781119296126.ch285

[15] C. Otten, U. Reisgen, S. Olschok, H. Fischer, and C. Panfil, Electron beam structuring of titanium materials for medical applications, In Proceedings of the 2nd International Electron Beam Welding Conference, p.106–107, (2012).

[16] L. Besra and M. Liu, A review on fundamentals and applications of electrophoretic deposition (EPD), Prog. Mater. Sci., vol. 52, no. 1, p.1–61, (2007).

[17] A. R. Boccaccini and I. Zhitomirsky, Application of electrophoretic and electrolytic deposition techniques in ceramics processing, Curr. Opin. Solid State Mater. Sci., vol. 6, p.251–260, (2002).

DOI: https://doi.org/10.1016/s1359-0286(02)00080-3

[18] L. Cordero-Arias, S. Cabanas-Polo, G. Haoxiang, J. Gilabert, E. Sanchez, J. A. Roether, D. W. Schubert, S. Viratanen, and A. R. Boccaccini, Electrophoretic deposition of nanostructured-TiO2/chitosan composite coatings on stainless steel, RSC Adv., vol. 3, p.11247–11254, (2013).

DOI: https://doi.org/10.1039/c3ra40535d

[19] Q. Chen, Y. Liu, Q. Q. Yao, S. S. Yu, K. Zheng, M. Pischetsrieder, and A. R. Boccaccini, Multilayerd bioactive composite coatings with drug delivery capability by electrophoretic deposition combined with layer-by-layer deposition, Adv. Biomater. Devices Med., vol. 1, p.18–27, (2014).

[20] A. R. Boccaccini, S. Keim, R. Ma, Y. Li, and I. Zhitomirsky, Electrophoretic deposition of biomaterials, J. R. Soc. Interface, vol. 7 Suppl 5, no. May, pp. S581–613, Oct. (2010).

DOI: https://doi.org/10.1098/rsif.2010.0156.focus

[21] F. Pishbin, a. Simchi, M. P. Ryan, and a. R. Boccaccini, Electrophoretic deposition of chitosan/45S5 Bioglass® composite coatings for orthopaedic applications, Surf. Coatings Technol., vol. 205, no. 23–24, p.5260–5268, (2011).

DOI: https://doi.org/10.1016/j.surfcoat.2011.05.026

[22] H. C. Hamaker, Formation o f a deposit, Trans. Faraday Soc., vol. 35, p.279–287, (1940).

Fetching data from Crossref.
This may take some time to load.