Mass-Producible Organic Nanocapsule with Water-Responsive Releasing Ability
An organic nanocapsule was obtained by mixing zinc acetate powder into a peptide lipid dispersion in ethanol. The nanocapsule was mass-produced at a scale of over 100 g L–1 within 1 h. Fourier transform infrared spectroscopy and scanning electron microscopy revealed that a zinc-peptide lipid complex was formed within 15 min, which subsequently transformed into a nanocapsule as a result of changes in the hydrogen bonding networks between the peptides. A variety of organic dyes could be encapsulated by simply adding them during the nanocapsule formation. We also confirmed their high stabilities in organic solvents, water-responsive morphological change, and resulting guest release. The water-responsive nanocapsule is expected to be useful in a variety of fields.
Prof. Kazuo Umemura
M. Kogiso et al., "Mass-Producible Organic Nanocapsule with Water-Responsive Releasing Ability", Materials Science Forum, Vol. 916, pp. 14-18, 2018