SAXS Study of Selected Cationic Surfactant Influence on the DSPC-Based Model Phospholipid System

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The phase behaviour of lipid bilayer systems prepared with 1,2-distearoyl-sn-glycero-3- phosphocholine (DSPC) with dodecyldimethyl(benzyloxymethyl)ammonium chloride (BzMDDAC) (at concentrations 0.1, 1 and 5%) has been studied by small angle X-ray scattering and differential scanning calorimetry. The SAXS and DSC results of the hydrated 10% DSPC revealed one typical phase transition corresponding to melting of the hydrocarbon chains at 55 °C. In the system of 10% DSPC - 0.1 % BzMDDAC the main transition was somewhat shifted towards lower temperatures, while at 1% concentration of BzMDDAC in the mixture, the lamellar phase disappeared, as evidenced by SAXS and DSC. The increase in BzMDDAC concentration to 5% in the mixture with 10% DSPC resulted in formation of a new lamellar phase.

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Periodical:

Solid State Phenomena (Volume 130)

Edited by:

Danuta Stróż & Małgorzata Karolus

Pages:

257-262

Citation:

M. Kozak et al., "SAXS Study of Selected Cationic Surfactant Influence on the DSPC-Based Model Phospholipid System", Solid State Phenomena, Vol. 130, pp. 257-262, 2007

Online since:

December 2007

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$38.00

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