Application of Glass Reinforced Hydroxyapatite Composite in the Treatment of Human Intrabony Periodontal Angular Defects – Two Case Reports

Abstract:

Article Preview

Bony defects caused by periodontitis are often treated by regenerative therapy using autografts and/or allografts. Alloplasts such as hydroxyapatite or ceramics and bioactive glasses are used as osteoconductive materials that serve as scaffold for new bony ingrowth. The purpose of this study was to ascertain the possible regenerative capability of glass reinforced hydroxyapatite (Bonelike¬)¬¬¬ an osteoconductive synthetic graft in the treatment of human periodontal intrabony angular defects. The material was placed in 2 defects in 2 individual patients and clinical parameters such as probing depth (PD) and clinical attachment level (CAL) have been included. Bone fill was determined using an intra oral periapical radiograph (IOPA) and Autocad Software. After 3 months implantation period, there was an improvement in CAL and reduction in PD along with bone fill was observed.

Info:

Periodical:

Solid State Phenomena (Volume 161)

Edited by:

Nandyala Sooraj Hussain and José Domingos Santos

Pages:

93-101

DOI:

10.4028/www.scientific.net/SSP.161.93

Citation:

G. Pavan Kumar et al., "Application of Glass Reinforced Hydroxyapatite Composite in the Treatment of Human Intrabony Periodontal Angular Defects – Two Case Reports ", Solid State Phenomena, Vol. 161, pp. 93-101, 2010

Online since:

June 2010

Export:

Price:

$35.00

[1] Genco RJ, Goldman HM, Cohen W, eds. Contemporary Periodontics. St. Louis: The CV mosby company.

[2] Karring T, Lindhe J, Cortellini P. Regenerative Periodontal therapy. In Lindhe J, Karring T, Lang NP, eds. Clinical periodontology and implant dentistry. Copenhagen: Munksgaard; 1997; 597-646.

[3] Froum SJ, Gomez C. Periodontal regeneration. Curr Opin Periodontol 1993: 111-128.

[4] Mellonig JT, Preuett AB, Moyer MP. HIV inactivation in a bone allograft. J Periodontol 1992; 63: 979-983.

[5] Becker W, Becker BE, Caffesse R. A comparison of demineralized freeze-dried bone and autogenous bone to induce bone formation in human extraction sockets. J Periodontol 1994; 65: 1128-1133. 6. Shetty V, Han TT. Alloplastic materials in reconstructive periodontal surgery. Dent Clin North Am 1991; 35: 521-530.

DOI: 10.1902/jop.1994.65.12.1128

[7] Stahl SS, Froum SJ. Histologic and clinical responses to porous hydroxylapatite implants in human periodontal defects. J Periodontol 1987; 58: 689-695.

DOI: 10.1902/jop.1987.58.10.689

[8] Stahl SS, Froum SJ. Human clinical and histologic responses to the placement of HTR polymer particles in 11 intrabony lesions. J Periodontol 1990; 61: 289-274.

[9] Baldock WT, Hutchens LH, McFall WT, Simpson DM. An evaluation of tricalcium phosphate implants in human periodontal osseous defects of two patients. J Periodontol 1985; 56: 1-8.

DOI: 10.1902/jop.1985.56.1.1

[10] Froum SJ, Stahl SS. Human intraosseous healing response in the placement of tricalcium phosphate ceramic implants. J Periodontol 1987; 58: 103-109.

DOI: 10.1902/jop.1987.58.2.103

[11] Hench LL, West JK. Biological application of bioactive glasses. Life Chem Rep 1996; 13: 187-241.

[12] Wilson J, Low SB. Bioactive ceramics for periodontal treatment-comparative studies in a patus monkey. J Appl Biomater 1992; 3; 123-129.

DOI: 10.1002/jab.770030208

[13] Wilson J, Merwin GE: Biomaterials for facial bone augmentation: Comparative studies. J Biomed Mater Res 1998; 22(suppl): 159-177.

[14] Wilson J, Clark AE, Hall M, Hench LL. Tissue response to bioglass endosseous ridge maintanence implants. J oral implantol, 1993: 4: 295-300.

[15] Wilson J, Pigott GH, Schoen FJ, Hench LL. Toxicology and biocompatibility of bioglasses. J biomed mater res 1981; 15; 805-817.

DOI: 10.1002/jbm.820150605

[16] Sousa RC, Lobato J. V, Sooraj Hussain N, Lopes MA, Maurício AC, Santos JD, J. Biomaterial Appl. 2008; 22: 373.

[17] Santos JD, Hastings GW, Knowles JC. Sintered HA compositions and methods for the preparation thereof, European patent WO 0068164.

[18] Santos, JD, Knowles JC, Reis R. L, Monteiro FJ, Biomaterials 1994; 15: 5.

[19] Santos JD, Lakhan JJ, Monterio FJ, Biomaterials 1995; 16: 521.

[20] Lopes M. A, Knowles JC, Santos, JD Monteiro FJ, Oslen I, Biomaterials 2000; 21: 1165.

[21] Lopes MA, Knowles JC, Santos JD, Montgeiro FJ, Oslen I, J. Biomed Mater Res. 1998, 41: 649.

[22] Ji Sook Park, Jon g-Jin Suh, Seong Ho-Choi et al: E ffe c t s of pretreatment clinical parameters on bioactive glass implantation in intrabony periodontal defects. J Periodontal 2001; 72: 730-740. 23. Froum SJ, Weinberg MA, Tarnow D: Comparison of bioactive synthetic bone graft particles and open flap debridement I the treatment of human periodontal defects- A clinical study. J Periodontol 1998; 69: 698-709.

DOI: 10.1902/jop.1998.69.6.698

[24] Zamet JS, Darbar UR, Griffith Gs et al: Particulate bioglass as a grafting material in the treatment of periodontal intrabony defects. J Clin Periodontol 1997: 24; 410-418.

DOI: 10.1111/j.1600-051x.1997.tb00205.x

[25] Green D, Walsh D, Mann S, Oraffo Roe. Potential of biomimesis in bone tissue engineering: Lessons from the design and synthesis of invertebrate skeketons. Bone 2002; 30: 810-815.

DOI: 10.1016/s8756-3282(02)00727-5

[26] Zaner DJ, Yukna RA. Particle size of periodontal bone grafting materials. J Periodontol 1984; 55: 406-409.

DOI: 10.1902/jop.1984.55.7.406

[27] Schepers EJC, Ducheyne P. The application of bioactive glass particles of narrow size range as a filler material for bone lesions: A 24 month animal experiment. Bioceramics 1993; 6: 401-404.

[28] Schepers EJC, Pinruethal P. A comparative study of bioactive glass and porous Hydroxylapatite particles in periodontal bone lesions. Bioceramics 1993; 5: 113-116.

[29] Hench LL, Paschall HA. Histochemical responses at a biomaterial's interface. J Biomed Mater Res 1974; 5: 49-64.

In order to see related information, you need to Login.