Papers by Author: Ju Ming Yao

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Authors: Yan Hong Zhang, Liang Jun Zhu, Ju Ming Yao
Abstract: Bone Morphogenetic Protein 2 (BMP-2) is a member of the transforming growth factor superfamily. It plays an important role in stimulating osteoblast differentiation and bone formation, and has been widely utilized in clinical bone repairing by implantation. In this study, the nano-hydroxyapatite (nHA)/silk fibroin (SF) porous scaffolds were fabricated for the sustained delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2), and then used to address the hypothesis that rhBMP-2 delivered from the scaffolds could enhance the bone formation in vitro. We optimized an effective method using a prokaryotic expression system to produce rhBMP-2. The rhBMP-2 was expressed, purified and renatured in vitro. And then the rhBMP-2 was loaded onto the nHA/SF scaffolds. The bioactivities of rhBMP-2-loaded nHA/SF scaffolds were assessed in vitro. The results showed that the rhBMP-2 promoted the osteoblasts adhesion and proliferation on the nHA/SF scaffolds. Also, the rhBMP-2 released from the nHA/SF scaffold stimulated a significant increase in alkaline phosphatase (ALP) activity of osteoblasts in vitro. These results demonstrated that the rhBMP-2-loaded nHA/SF scaffolds could promote the bone regeneration and showed potential applications in the bone tissue engineering.
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Authors: Cai Qian Zhang, Li Qin Lou, Ju Ming Yao
Abstract: With the classical mechanics principle, fluid mechanics principle and capillary conduction theory, the six parties and four parties loosen state model of yarn were established. The conclusions as migration distance liquid in yarn vs mean velocity is inversely proportion when the liquid in capillary is free of gravity. Liquid mean velocity of four parties loosen state model is twice of the velocity of six parties’; The lager volume filling rate of yarn has less liquid conduction ability.
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Authors: Lin Liu, Ju Ming Yao
Abstract: In this paper, the cellulose whisker/silk fibroin (CW/SF) aqueous solution with different composition was obtained by a dialysis against polyethylene glycol (PEG) solution at room temperature. The rheological behavior of CW/SF solution was investigated and the reinforced CW/SF hybrid fibres were prepared by a dry-wet spinning method. The results showed that the spinnability was better for the CW/SF solution according to the calculation of flowing characteristic index. The cellulose whiskers were dispersed homogeneously in the silk matrix. Moreover, it could be found that the tensile strength and Young’s modulus of the hybrid fibers were improved with the increase of cellulose whisker content, which reached the maximum when the cellulose whisker content was 5 wt%. Compared with the pure silk fiber, the tensile strength and Young’s modulus of the CW/SF hybrid fibers containing 5 wt% CWs were increased from 135.78±12.73 MPa and 5.74±0.43 GPa to 438.68±22.63 MPa and 17.36±2.04 GPa, respectively.
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Authors: Cai Qian Zhang, Ju Ming Yao
Abstract: The wicking properties of porous polyester, Coolmax and conventional polyester rotor yarns were tested with the capillary flow of a colored liquid and the height was recorded against the time. The relations of material structure, temperature, and yarn count factors to wicking properties were discussed. Results showed that: the moisture conduction of porous structure yarns were best of all yarns; Higher temperature results the faster of wicking speed, and is especially for porous polyester; The finer Coolmax and conventional polyester rotor yarns are of faster wicking speed, but this rule is not distinct for porous structure polyester.
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