Papers by Author: Hye Ryeon Lim

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Authors: Yeon I Woo, Hyun Joo Son, Hye Ryeon Lim, Mi Hee Lee, Hyun Sook Baek, Kazufumi Tsubaki, Jong Chul Park
Abstract: Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.
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Authors: Jin Hyun Chung, Hye Ryeon Lim, Tek Hyung Lee, Mi Hee Lee, Yeon I Woo, Hyun Sook Baek, Seung Jin Lee, Jeong Koo Kim, Jong Chul Park
Abstract: Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.
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Authors: Hye Ryeon Lim, Hyun Sook Baek, Mi Hee Lee, Yeon I Woo, Tek Hyung Lee, Jong Chul Park
Abstract: Adhesions are abnormal attachments between tissues, caused by an inflammatory stimulus or trauma. It was generally used physical barriers and various agents to prevent from adhesions formation. In this study, we made an experiment on animals with wound covering material of substance to prevent tissue adhesion. It was performed in sub-acute toxicity, and tested local effects after implantation.
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