Papers by Keyword: Antibacterial

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Authors: Leila Zarei, Sheila Shahidi, Seyed Mohammad Elahi, Arash Boochani
Abstract: Researches show that properties of semiconductor materials such as electrical, optical and antibacterial properties can be improved in the nanoscale. Among the semiconductor materials , zinc oxide with excellent electronic properties has been considered extremely. Application and properties of Zno nanoparticles depends on the size and morphology. In the present work, Zno Nanoparticles (NPs) were prepared by sonochemical method at a constant temperature and were applied on to the 100% cotton woven fabric using Insitu method. The results show that nanoparticles with average sizes of 20-100 nm with different morphologies were created on the surface of samples. Synthesis of ZnO-NPs were varied in the morphological transformation by changes in zinc acetate concentration. Characterizations were carried out, Scanning electron microscopy (SEM) and Spectrophotometery. The antibacterial activities of the fabrics were assessed semi-quantitatively by the coloneis count method. The results show that the finished fabric demonstrated significant antibacterial activity against S.aureus in antibacterial test.
Authors: Xiao Jie Lian, Xu Mei Wang, Fu Zhai Cui
Abstract: In the present study, a new antibacterial bone graft substitute has been developed for repairing bone defects and inhibiting related infections at the same time. Calcium sulphate hemihydrate (CSH) was introduced into nanohydroxyapatite/collagen (nHAC) to prepare a self-setting in situ bone repair materials. The nHAC/CSH was used as a carrier of vancomycin (VCM) for anti-infection and the treatment of osteomyelitis. The VCM/nHAC/CSH composite was a porous scaffold with porosity of 38.8% and the compressive mechanical strength was about 4.8 MPa. The final setting time was about 15~20 min. The inhibition ratio of VCM/nHAC/CSH was more than 99.8% and the distinct inhibition zone of 18 mm was formed in Staphylococcus aureus bacterium incubation dish with VCM/nHAC/CSH disc in the center of agar matrix for 16 hours of incubation. After incubating 17 days at 37 in vitro, the concentration of vancomycin in elution fluild was around 12 μg/mL. Therefore, the VCM/nHAC/CSH bone substitute presents ideal self-setting antibacterial, cytocompatibility, sustained release properties and has great potential applications for the treatment of bone defect-related infection in orthopedic surgeries.
Authors: R. Yuvakkumar, J. Suresh, A. Joseph Nathanael, M. Sundrarajan, Sun Ig Hong
Abstract: The effects of ZnO and CuO nanoparticles on antibacterial and wash durability behaviour of nanoparticles treated cotton fabric using sodium alginate as cross linker were studied. The metal oxide nanoparticles treated cotton fabric using sodium alginate as a crosslinker was characterized employing SEM-EDX and their antibacterial activity was analyzed. The obtained zone of inhibition and estimated wash durability behaviour is in the order of ZnO>CuO.
Authors: M. Bellantone, N.J. Coleman, Larry L. Hench
Authors: Zafer Alajmi, Tao Fu, Yan Tao Zhao, Shui Yun Yang, Jia Mao Sun
Abstract: MgO and silver-containing MgO (AgMgO, 3.3, 9.1 at% Ag) films were sol-gel coated on titanium to improve its antibacterial property. Thermal analyses of MgAc2·4H2O powder revealed that MgO was crystallized at 400 °C. X-ray diffraction analysis showed that MgO was converted to Mg(OH)2 or Mg5(CO3)4(OH)2·4H2O during the ageing in air. Silver nanoparticles at the surface of AgMgO films were identified by scanning electron microscopy and x-ray photoelectron spectroscopy. The MgO film was about 1.5 um thick. The potentiodynamic polarization test in the Ca-free Hank’s balanced salt solution showed that the coated titanium samples had better corrosion resistance than the polished one. The dissolution of silver nanoparticles resulted in a current peak in the polarization plots. In the antibacterial test against E. Coli, the inhibition zone width was 0.3, 1.6, 2.0 mm for the films with 0, 3.3, 9.1 at% Ag, respectively. The bactericidal mechanisms of the MgO and AgMgO films were discussed. The present work would provide a facile method for antibacterial surface modification of titanium based osteo-implants.
Authors: Mohsen Mehregan, Hossein Soltaninejad, Behnaz Toluei Nia, Hadi Zare-Zardini, Masoud Zare-Shehneh, Leila Ebrahimi
Abstract: The formation of biofilm (Biofouling) in different surface is the great concern in types of fields, especially in medical and health system as well as in membrane technology. The present study deals with the synthesis and characterization of Al2O3 nanopowders with antibacterial activity which can be a potentially utilized material for biocompatible implants. Nanostructure was synthesized based on sol-gel method and then, crystallite size, and microstructural and morphological characterization of nanostructure were determined by X-ray diffraction, electron-microscopic techniques - scanning electron microscopy (SEM) and transmission electron microscopy (TEM). According to X-ray diffraction, the value of particle size for Al2O3 nanopowders is 20.85 nm. In the following, the antibacterial activity of Al2O3 nanoparticles was assessed on three gram positive and three gram negative bacteria by radial diffusion assay and measurement of minimum inhibitory concentration (MIC). The toxicity of Al2O3 nanopowders on blood cells was also assessed. The results showed that this nanostructure has potent antibacterial activity against gram positive and gram negative bacteria. The synthesized Al2O3 nanopowders showed the antimicrobial activity against antibiotic resistant bacterium, Staphylococcus aureus. Significant antibacterial activity of this nanostructure was seen to have a greatest effect on Bacillus cereus with the MIC value of 9.2 μg/ml; while, among bacterial strains, Salmonella typhimurium was investigated to be the most resistant one with the MIC of 35.6 μg/ml. Al2O3 nanopowders showed no toxicity on blood cells. according to acquired data in this study, Al2O3 nanopowders may be a good material for inhibition of biofilm formation.
Authors: Qian Wang, Ke Gong, Cheng Bo Cao, Jing Guo, Xiao Jiao Wang
Abstract: A new antibacterial acellular dermal matrix (AADM) dressing can not only resist infection, but also accelerate wound healing. AADM was prepared by SDS (0.40%), trypsin (0.40%) and keratin (0.30%), and then cross-linked with carboxymethyl chitosan (1%) with glutaraldehyde, whose tensile strength (MPa) is 10.66, thickness (mm), 0.53, the rate of permeable steam (g • m-2 • 24h-1), 3640, porosity (%), 81, degradation time in vitro (h), 24.33, pH, 6.5, and the average inhibition rate, more than 70%. At the same time, scanning electron microscopy showed that the structure of AADM was evacuated and the pores were interconnected. On such basis, a conclusion was drawn: the properties of AADM has been sharply increased, compared with acellular dermal matrix, which cannot resist infection, and the new antibacterial acellular dermal matrix completely meets the clinical requirements for burn dressings.
Authors: Fei Fei Wang, Ziang Yao, Hai Ge Wu, Sheng Xia Zhang, Nan Nan Zhu, Xue Gai
Abstract: Κ-carrageenan oligosaccharides were prepared by enzymatic degradation. The inhibiting activities of the prepared κ-carrageenan oligosaccharides against Escherichia coli (E.coli ), Staphylococcus aureus (S.aureus), Saccharomyces cerevisiae (S.cere), Penicillium citrinum (P.citr) and Mucor.sp were determined and compared by measuring the inhibitory zone diameter. The results indicate that all tested κ-carrageenan oligosaccharides have inhibiting activity against the five bacteria, but the inhibiting activities against Saccharomyces cerevisiae is higher than against any other four bacteria. The inhibiting concentration (MIC) of κ-carrageenan oligosaccharides are 1mg/ml, 5mg/ml, 20mg/ml, and antibacterial activity of κ-carrageenan oligosaccharides was inversely affected by concentration, with the highest activity at the concentration of 5mg/ml.
Authors: M.H.M. Amini, Rokiah Hashim, Nurul Syuhada Sulaiman, O. Sulaiman, S.F. Sulaiman, F. Abood, F. Kawamura, R. Wahab, M. Mohamed, M.S.M. Rasat
Abstract: Cerbera odollam’s tree parts were extracted with methanol and further fractionated using n-hexane, ethyl acetate and ethanol, followed by antibacterial assay against Bacillus subtilis, Bacillus licheniformis, Escherichia coli and Pseudomonas aeruginosa. Hexane soluble parts from flower, fruit, leaf, wood, bark and ethyl acetate soluble part from bark showed antibacterial activity against Bacillus subtilis. Hexane soluble parts from leaf and bark and ethyl acetate soluble parts from wood showed antibacterial activity against Bacillus licheniformis. All fractions appeared ineffective on Escherichia coli and Pseudomonas aeruginosa. Screened extracts were analysed using FTIR. Experiments were continued with impregnation of methanolic extracts of Cerbera odollam into Melamine-urea formaldehyde (MUF) particleboards, Phenol-resorcinol formaldehyde (PRF) particleboards and solid wood samples followed by exposure to wood-boring beetles and natural decaying.
Authors: Fei Ling Sun, Min Zheng
Abstract: Modified polyester fabric with pores was treated with self-synthesized TiO2 under high-temperature (130°C) and high-pressure condition via one-bath process. By SEM, uniform holes and many particles could be seen on the treated fiber surface. EDX was used for analysis. Results show that materials deposited on the fiber surface were TiO2. Shake flask test was selected to evaluate the antibacterial ability of the treated fabric. Antibacterial rate against E.coli and S.aureus were 96.24% and 92.00%, respectively. At the same time, the durability to laundering was also tested. The results indicated that antibacterial property of the treated fabric was still excellent even after it was washed 50 times
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