Papers by Keyword: Dicalcium Phosphate Anhydrate

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Authors: Akari Takeuchi, Akinari Nakagawa, Shigeki Matsuya, Ishikawa Kunio
Abstract: Effect of added α-tricalcium phosphate (α-TCP) and β-TCP was investigated to understand the setting reaction of apatite cement consisting of tetracalcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA). Addition of TCP delayed the initial setting time because TCP was not involved in the initial setting reaction and resulted in the decreased initial mechanical strength. After the initial setting of the cement due to the conversion of TTCP and DCPA into apatite, α-TCP dissolved to supply calcium and phosphate ions and they were consumed for crystal growth of apatite. Therefore, mechanical strength of the apatite cement containing α-TCP was increased. In contrast, added β-TCP showed no reactivity in the cement and thus result in the decreased mechanical strength.
Authors: Hajime Ohsawa, Atsuo Ito, Yu Sogo, Atsushi Yamazaki, Tadao Ohno
Abstract: Highly disgregated dicalcium phosphate anhydrate (DCP) nanoparticles 240-367 nm in diameter were synthesized by a reaction between calcium carbonate and phosphoric acid. When the DCP nanoparticles were immersed in a supersaturated calcium phosphate solution containing bovine serum albumin (BSA) and ethanol, BSA/DCP nano-composite particles were synthesized through the coprecipitation of BSA on the DCP nanoparticles. BSA was firmly immobilized on the BSA/DCP nano-composite particles. The results of this study suggest that DCP nanoparticles appear to be useful as a drug delivery vehicle.
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