Apatite-Coated Poly(lactic acid) Composites with Cell-Compatibility Prepared by a Biomimetic Method

Hirotaka Maeda; Toshihiro Kasuga

doi:10.4028/www.scientific.net/AMR.11-12.239

Paper Titles

Preparation of Macroporous Glass-Ceramic Composites Containing β-TCP
p.223

Preparation of Bimodal Porous Biphasic Calcium Phosphate Ceramics and Their Dissolution Behavior in Simulated Body Fluid
p.227

Particle Size Control in Sol-Gel Synthesis of Nano Hydroxyapatite
p.231

Amorphous Calcium Silicate Coating on Metallic Titanium
p.235

Apatite-Coated Poly(lactic acid) Composites with Cell-Compatibility Prepared by a Biomimetic Method
p.239

PLLA/HA Electrospin Hybrid Nanofiber Scaffolds: Morphology, In Vitro Degradation and Cell Culture Potential
p.243

Porous Apatite Ceramics Derived from Woods
p.247

Selective Adsorption of Microorganisms onto Artificial Siderophore-Modified Glass Surface
p.251

SiCOI Structure Fabricated by Hot-Mesh Chemical Vapor Deposition
p.257

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 11-12Apatite-Coated Poly(lactic acid) Composites with...

Apatite-Coated Poly(lactic acid) Composites with Cell-Compatibility Prepared by a Biomimetic Method

Abstract:

A new type of poly(lactic acid) (PLA)/calcium carbonates hybrid membrane incorporated with silicon, which is suggested to stimulate the formation of bones, was prepared using aminopropyltriethoxysilane (APTES) for bone repair materials. Carboxyl groups in PLA made a chemical bond with amino groups in APTES, resulting in the formation of the hybrid membrane. The membrane formed hydroxycarbonate apatite (HCA) on its surface after 3 days of soaking in simulated body fluid (SBF). X-ray energy dispersive spectroscopy showed the HCA layer includes Si with Ca and P. A result of osteoblast-like cellular proliferation on the substrates that the membrane coated with silicon-containing HCA had much higher cell-proliferation ability than the membrane.