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Self-Setting Biphase Porous Calcium Phosphate Cement
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Effects of Setting Liquid on α-Calcium Phosphate-Tetracalcium Phosphate Bone Cement
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In Vivo Behavior of Injectable Fast-Setting Calcium Phosphate Cement
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Characterization of Porous Calcium Phosphate Bioceramics Modified by Porosifier

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Abstract:

The porous structure of calcium phosphate ceramics is one of the essential conditions resulting in bone formation. The porous structure of biphasic HA/β-TCP ceramics was improved by adding microporous porosifer and the porous characteristics such as porosity, pore size and pore size distribution were determined by the mercury intrusion porosimetry, the cell culture in vitro and the animal experiment. By means of SEM and fluorescence decoration, cells were observed firstly attaching the edge of macropores of specimens and the wall of the macropores with micropores when co-cultured with HA/β-TCP ceramics. The specimens were also implanted in dorsal muscles of healthy dogs for 1.5and 3 months. More bone formation in the specimen with microporous porosifer was found by histological observation after taking out. It suggested that the micropores in the walls of macropores of bioceramics had important effect upon their osteoinduction.

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Periodical:

Key Engineering Materials (Volumes 336-338)

Pages:

1618-1621

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.336-338.1618

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Online since:

April 2007

Authors:

Li Gou, Shun Qiao Cheng, Jun Guo Ran, Bao Hui Su

Keywords:

Bioceramic, Calcium Phosphate, Osteoinductivity, Porosifier

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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