Comparison of Biomineralization on Calcium Phosphate Implants in Rabbit and Dog Models

Ren Long Xin; Yang Leng; Ji Yong Chen; Xiu Dong Yang

doi:10.4028/www.scientific.net/KEM.330-332.27

Paper Titles

In Situ Micro-XRD Structure Analysis of Bioapatite in Human Ribs
p.11

Preparation of β-Calcium Metaphosphate (β-CMP) Whiskers
p.15

Comparison of Carbonate Hydroxyapatite with and without Sodium Co-Substitution
p.19

Biocompatibility of Calcium Phosphate Ceramics Synthesized from Eggshell
p.23

Comparison of Biomineralization on Calcium Phosphate Implants in Rabbit and Dog Models
p.27

Dissolution of Hydroxyapatite Reinforced Grain Boundary by Glassy Phases
p.31

Chemical Dissolution and Bone Formation in Identical Porous β-TCP and HA
p.35

Studies on Non-Quenched Calcium Phosphate Cement: Influences of Quenching and Milling on Setting Characteristic
p.39

Improvement of Microstructure of Bovine Hydroxyapatite (BHA) by Doping with Calcium Fluoride
p.43

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Comparison of Biomineralization on Calcium Phosphate Implants in Rabbit and Dog Models

Abstract:

Porous alpha- tricalcium phosphate (α-TCP) was implanted in rabbit and dog models to investigate its induction of calcium phosphate (Ca-P) formation. The morphology and structure of the formed Ca-Ps were examined using scanning electron microscopy (SEM) and transmission electron microscopy (TEM), respectively. The results showed an animal-dependent behavior of in vivo Ca-P formation. There were flake-like octacalcium phosphate (OCP) precipitates in the rabbit but rod-like hydroxyapatite (HA) precipitates in the dog model. In addition, high-resolution TEM (HRTEM) image revealed that there was OCP structure in certain portions of the rod-like HA precipitates in the dog model. And the orientation relation of OCP/HA was deduced as OCP (010)//HA (0 10) and OCP (001)//HA (00 1) . This implied that the in vivo HA was formed via OCP precursor phase.