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The Influence of Bovine Serum Albumin on the Biomimetic Calcium Phosphate Coating of Bioactivated Titanium

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Abstract:

In this study, bovine serum albumin protein (BSA) was introduced to investigate the co-precipitation process of calcium phosphate and BSA on bioactivated Ti. Commercially pure titanium were bioactivated firstly, and then immersed in a highly supersaturated stable calcium phosphate (Ca-P) solution at three different conditions. The samples designated as Ti-C, Ti-C-CB, and Ti-C-B for control. The samples were evaluated by SEM with EDX, XRD and XPS. The co-precipitation of BSA protein and Ca-P influenced the morphology of the crystals of Ti-C-CB significantly. In terms of the immersion in the Ca-P solution containing BSA, the co-precipitation of Ca-P with BSA on the surface of Ti-C-CB was a chemical process rather than simple physical adsorption, which was most possibly achieved by the linkage of –COO− groups to Ca-P. Such coprecipitated interaction led to the formation of a tight, dense and uniform Ca-P coating.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

581-584

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.581

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Online since:

February 2007

Authors:

Yao Wu, Bang Cheng Yang, Jian Lu, Zhong Wei Gu, Xing Dong Zhang

Keywords:

Biomimetic, Bovine Serum Albumin (BSA), CaP Coating, Co-Precipitation, Titanium (Ti)

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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