Collagenous Molecule Immobilization on Hydroxyapatite Surface

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Abstract:

Collagenous molecule was successfully immobilized to hydroxyapatite (HA) surface through a molecular bridge (2-Hydroxyethyl acrylate, HEMA) that was grafted to the surface with covalent bond by gamma irradiation. Hydroxyapatite modified by atelocollagen had been characterized by several surface sensitive techniques, such as FT-IR, SEM, XPS. The investigations showed that the collagen, a bioactive macromolecule, was immobilized on the HA surface through covalent bond.

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Periodical:

Key Engineering Materials (Volumes 330-332)

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741-744

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February 2007

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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[1] T.P. Schmalzried, M . Jasty, W.H. Harris: J. Bone Joint Surg. Am. 74-A(1992), p.849.

Google Scholar

[2] W.H. Harris: Clin. Orthop. 311(1995), p.46.

Google Scholar

[3] J. Wilson, S.B. Low: J. Appl. Biomater. 3(1992), p.123.

Google Scholar

[4] R. Labella, M. Braden, S. Deb: Biomaterials 15(1992), p.1197.

Google Scholar

[5] T. Suzuki, M. Toyiyama, Y. Kwamoto, Y. Yokogawa: J. Fermentation Bioengng. 70(1990), p.164.

Google Scholar

[6] K. Nishizawa, M. Toriyama, T. Suzuki, Y. Kawamoto: Chem. Soc. Japan. 1(1995), p.63.

Google Scholar