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Effect of Inorganic Ions on Morphology and Crystallinity of Collagen Fibrils

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Abstract:

As a natural biomaterial, collagen especially pepsin-solubilized collagen (type I) has been used widely in biomedical fields due to its excellent biocompatibility. In this preliminary study, we investigate the effect of some inorganic ions which are frequently utilized in the preparation of collagen on the morphology and crystallinity of fibrils. The scanning electron microscope and x-ray diffraction were applied to analyze the morphology and the crystallization of the reconstituted collagen fibrils, respectively. Although further studies are needed, these initial results indicate that by controlling the self-assembly conditions of collagen molecules, we may achieve the desired properties of fibrillar collagen products.

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Advanced Biomaterials VII View Preview

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Periodical:

Key Engineering Materials (Volumes 342-343)

Pages:

929-932

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.342-343.929

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Online since:

July 2007

Authors:

Qing Rong Wei, Xiu Dong Yang, Jian Lu, Bo Zhang, Bo Jiang, Hong Song Fan, Ji Yong Chen, Zhong Wei Gu, Xing Dong Zhang

Keywords:

Collagen Fibril, Crystallinity, Inorganic Ions, Morpholoy

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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